Language

English

Publication Date

2-7-2023

Journal

Cell Metabolism

DOI

10.1016/j.cmet.2023.01.007

PMID

36754017

PubMedCentral® Posted Date

2-7-2023

PubMedCentral® Full Text Version

Post-print

Abstract

In Nature Medicine, Surendran and colleagues recently reported the analysis of human plasma metabolomic data for 913 metabolites in ∼20,000 individuals, identifying 2,599 metabolite-genetic variant associations and >400 metabolite signatures comprised of jointly regulated metabolites. This extensive atlas of variant-metabolite relationships reveals novel genomic mechanisms driving metabolic phenotypes.

Keywords

Humans, Metabolomics, Metabolome, Phenotype

Published Open-Access

yes

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