Language
English
Publication Date
3-27-2024
Journal
Briefings in Bioinformatics
DOI
10.1093/bib/bbae122
PMID
38555475
PMCID
PMC10981671
PubMedCentral® Posted Date
3-28-2024
PubMedCentral® Full Text Version
Post-print
Abstract
The lack of interoperable data standards among reference genome data-sharing platforms inhibits cross-platform analysis while increasing the risk of data provenance loss. Here, we describe the FAIR bioHeaders Reference genome (FHR), a metadata standard guided by the principles of Findability, Accessibility, Interoperability and Reuse (FAIR) in addition to the principles of Transparency, Responsibility, User focus, Sustainability and Technology. The objective of FHR is to provide an extensive set of data serialisation methods and minimum data field requirements while still maintaining extensibility, flexibility and expressivity in an increasingly decentralised genomic data ecosystem. The effort needed to implement FHR is low; FHR's design philosophy ensures easy implementation while retaining the benefits gained from recording both machine and human-readable provenance.
Keywords
Humans, Genome, Genomics, Information Dissemination, Software, Reference Genome, provenance, data management, network effect, FASTA
Published Open-Access
yes
Recommended Citation
Wright, Adam; Wilkinson, Mark D; Mungall, Christopher; et al., "FAIR Header Reference Genome: A TRUSTworthy Standard" (2024). Faculty and Staff Publications. 5989.
https://digitalcommons.library.tmc.edu/baylor_docs/5989