Publication Date
8-1-2024
Journal
The Texas Heart Journal
DOI
10.14503/THIJ-24-8423
PMID
39086311
Publication Date(s)
July-December 2024
Language
English
PMCID
PMC11292115
PubMedCentral® Posted Date
8-1-2024
PubMedCentral® Full Text Version
Post-Print
Published Open-Access
yes
Keywords
Humans, Cardiomyopathy, Hypertrophic, Ablation Techniques, Male, Treatment Outcome, Ethanol, Middle Aged
Copyright
This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.
Abstract
Despite substantial advances in the management of hypertrophic cardiomyopathy, advanced heart failure remains a major cause of morbidity in this patient population. This narrative review presents the case of a patient with hypertrophic obstructive cardiomyopathy who underwent alcohol septal ablation to frame a discussion of modern therapies for hypertrophic cardiomyopathy. The current treatment landscape includes medications, both old and new, and surgical and procedural interventions to relieve mechanical obstruction. Several promising new modalities for relieving obstruction are in the nascent stages of development.