Publication Date

8-1-2024

Journal

The Texas Heart Journal

DOI

10.14503/THIJ-24-8423

PMID

39086311

Publication Date(s)

July-December, 2024

Language

English

PMCID

PMC11292115

PubMedCentral® Posted Date

8-1-2024

PubMedCentral® Full Text Version

Post-print

Published Open-Access

yes

Keywords

Humans, Cardiomyopathy, Hypertrophic, Ablation Techniques, Male, Treatment Outcome, Ethanol, Middle Aged, Cardiomyopathy, hypertrophic; ablation techniques; radiosurgery

Abstract

Despite substantial advances in the management of hypertrophic cardiomyopathy, advanced heart failure remains a major cause of morbidity in this patient population. This narrative review presents the case of a patient with hypertrophic obstructive cardiomyopathy who underwent alcohol septal ablation to frame a discussion of modern therapies for hypertrophic cardiomyopathy. The current treatment landscape includes medications, both old and new, and surgical and procedural interventions to relieve mechanical obstruction. Several promising new modalities for relieving obstruction are in the nascent stages of development.

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