Publication Date
4-1-2020
Journal
The Texas Heart Institute Journal
DOI
10.14503/THIJ-18-6736
PMID
32603473
Publication Date(s)
April 2020
Language
English
PMCID
PMC7328079
PubMedCentral® Posted Date
6-17-2020
PubMedCentral® Full Text Version
Post-Print
Published Open-Access
yes
Keywords
Cardiology, Cardiovascular Diseases, Echocardiography, Humans, Medical Oncology, Neoplasms
Copyright
This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.
Abstract
Speckle-tracking echocardiography has enabled clinicians to detect changes in myocardial function with more sensitivity than that afforded by traditional diastolic and systolic functional measurements, including left ventricular ejection fraction. Speckle-tracking echocardiography enables evaluation of myocardial strain in terms of strain (percent change in length of a myocardial segment relative to its length at baseline) and strain rate (strain per unit of time). Both measurements have potential for use in diagnosing and monitoring the cardiovascular side effects of cancer therapy. Regional and global strain measurements can independently predict outcomes not only in patients who experience cardiovascular complications of cancer and cancer therapy, but also in patients with a variety of other clinical conditions. This review and case series examine the clinical applications and overall usefulness of speckle-tracking echocardiography in cardio-oncology and, more broadly, in clinical cardiology.