Author ORCID Identifier
0000-0003-1624-8329
Date of Graduation
5-2021
Document Type
Dissertation (PhD)
Program Affiliation
Neuroscience
Degree Name
Doctor of Philosophy (PhD)
Advisor/Committee Chair
Nitin Tandon
Committee Member
Edgar Walters
Committee Member
Xaq Pitkow
Committee Member
Simon Fischer-Baum
Committee Member
Valentin Dragoi
Abstract
The human capability for fluent speech profoundly directs inter-personal communication and, by extension, self-expression. Language is lost in millions of people each year due to trauma, stroke, neurodegeneration, and neoplasms with devastating impact to social interaction and quality of life. The following investigations were designed to elucidate the neurobiological foundation of speech production, building towards a universal cognitive model of language in the brain. Understanding the dynamical mechanisms supporting cortical network behavior will significantly advance the understanding of how both focal and disconnection injuries yield neurological deficits, informing the development of therapeutic approaches.
Keywords
language, neurobiology, electrocorticography, production, perception, stimulation, fMRI, DTI
Included in
Cognitive Neuroscience Commons, Computational Neuroscience Commons, Dynamical Systems Commons, Medicine and Health Sciences Commons, Signal Processing Commons, Systems Neuroscience Commons