Faculty, Staff and Student Publications

Authors

    Language

    English

    Publication Date

    4-25-2024

    Journal

    Scientific Reports

    DOI

    10.1038/s41598-024-60094-7

    PMID

    38664463

    PMCID

    PMC11045861

    PubMedCentral® Posted Date

    4-25-2024

    PubMedCentral® Full Text Version

    Post-print

    Abstract

    The present study examined the role of age and sex in the outcomes of non-surgical periodontal therapy (NSPT). De-identified demographic and periodontal characteristics of patients who presented for baseline periodontal evaluation, NSPT, and periodontal re-evaluation were abstracted from electronic health records. Independent associations of age and sex with severe periodontitis defined as ≥ 5 mm clinical attachment loss (CAL) and ≥ 6 mm probing depth (PD) were determined using multinomial logistic regression. The null hypothesis was rejected at α <  0.05. A total of 2866 eligible subjects were included in the analysis. Significantly lower odds of CAL ≤ 4 mm than CAL ≥ 5 mm (reference) were observed in adults aged 35-64 (odds ratio, OR, 0.19; 95% confidence interval, CI 0.13, 0.29) and ≥ 65 years (OR 0.13; 95% CI 0.07, 0.25) compared to those aged 18-34 years. Odds of PD <  4 mm versus PD ≥ 6 mm (reference) were lower in adults aged 35-64 years than those aged 18-34 years (OR 0.71; 95% CI 0.55, 0.90) and higher in females compared to males (OR 1.67; 95% CI 1.14, 2.44). These results suggest more compromised post-NSPT outcomes in older adults and males compared to the respective populations and highlight the need for personalized therapeutic strategies in these populations.

    Keywords

    Humans, Male, Female, Middle Aged, Adult, Retrospective Studies, Age Factors, Sex Factors, Aged, Young Adult, Adolescent, Treatment Outcome, Periodontitis, Aging, Association, Sex, Periodontitis, Treatment outcome, Periodontitis, Dental epidemiology

    Published Open-Access

    yes

    Included in

    Dentistry Commons

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