A Retrospective Analysis of the Role of Age and Sex in Outcomes of Non-surgical Periodontal Therapy at a Single Academic Dental Center

Authors

• Nikola Angelov
• Nikolaos Soldatos
• Effie Ioannidou
• Tonia C Carter
• Neel Shimpi
• Joseph Applegate
• Krishna Kumar Kookal
• Karo Parsegian

Language

English

Publication Date

4-25-2024

Journal

Scientific Reports

DOI

10.1038/s41598-024-60094-7

PMID

38664463

PMCID

PMC11045861

PubMedCentral® Posted Date

4-25-2024

PubMedCentral® Full Text Version

Post-print

Abstract

The present study examined the role of age and sex in the outcomes of non-surgical periodontal therapy (NSPT). De-identified demographic and periodontal characteristics of patients who presented for baseline periodontal evaluation, NSPT, and periodontal re-evaluation were abstracted from electronic health records. Independent associations of age and sex with severe periodontitis defined as ≥ 5 mm clinical attachment loss (CAL) and ≥ 6 mm probing depth (PD) were determined using multinomial logistic regression. The null hypothesis was rejected at α <  0.05. A total of 2866 eligible subjects were included in the analysis. Significantly lower odds of CAL ≤ 4 mm than CAL ≥ 5 mm (reference) were observed in adults aged 35-64 (odds ratio, OR, 0.19; 95% confidence interval, CI 0.13, 0.29) and ≥ 65 years (OR 0.13; 95% CI 0.07, 0.25) compared to those aged 18-34 years. Odds of PD <  4 mm versus PD ≥ 6 mm (reference) were lower in adults aged 35-64 years than those aged 18-34 years (OR 0.71; 95% CI 0.55, 0.90) and higher in females compared to males (OR 1.67; 95% CI 1.14, 2.44). These results suggest more compromised post-NSPT outcomes in older adults and males compared to the respective populations and highlight the need for personalized therapeutic strategies in these populations.

Keywords

Humans, Male, Female, Middle Aged, Adult, Retrospective Studies, Age Factors, Sex Factors, Aged, Young Adult, Adolescent, Treatment Outcome, Periodontitis, Aging, Association, Sex, Periodontitis, Treatment outcome, Periodontitis, Dental epidemiology

Published Open-Access

yes

Recommended Citation

Angelov, Nikola; Soldatos, Nikolaos; Ioannidou, Effie; et al., "A Retrospective Analysis of the Role of Age and Sex in Outcomes of Non-surgical Periodontal Therapy at a Single Academic Dental Center" (2024). Faculty, Staff and Student Publications. 177.
https://digitalcommons.library.tmc.edu/uthdb_docs/177