Faculty, Staff and Student Publications
Publication Date
4-13-2023
Journal
Cell
Abstract
Intercellular communication is a key feature of cancer progression and metastasis. Extracellular vesicles (EVs) are generated by all cells, including cancer cells, and recent studies have identified EVs as key mediators of cell-cell communication via packaging and transfer of bioactive constituents to impact the biology and function of cancer cells and cells of the tumor microenvironment. Here, we review recent advances in understanding the functional contribution of EVs to cancer progression and metastasis, as cancer biomarkers, and the development of cancer therapeutics.
Keywords
Humans, Neoplasms, Extracellular Vesicles, Cell Communication, Biomarkers, Tumor, Tumor Microenvironment
DOI
10.1016/j.cell.2023.03.010
PMID
37059067
PMCID
PMC10484374
PubMedCentral® Posted Date
April 2024
PubMedCentral® Full Text Version
Author MSS
Published Open-Access
yes
Included in
Bioinformatics Commons, Biomedical Informatics Commons, Medical Sciences Commons, Oncology Commons