Faculty, Staff and Student Publications
Publication Date
4-1-2023
Journal
Neuro-Oncology-Practice
DOI
10.1093/nop/npac095
PMID
36970170
PMCID
PMC10037943
PubMedCentral® Posted Date
December 2022
PubMedCentral® Full Text Version
Post-print
Abstract
BACKGROUND: Improvements in therapies have led to an increasing number of long-term survivors of brain metastases. The present series compares a population of 5-year survivors of brain metastases to a generalized brain metastases population to assess for factors attributable to long-term survival.
METHODS: A single institution retrospective review was performed to identify 5-year survivors of brain metastases who received stereotactic radiosurgery (SRS). A historical control population of 737 patients with brain metastases was used to assess similarities and differences between the long-term survivor population and the general population treated with SRS.
RESULTS: A total of 98 patients with brain metastases were found to have survived over 60 months. No differences between long-term survivors and controls were identified with regards to the age at first SRS (
CONCLUSION: Five-year survivors of brain metastases represent a diverse histologic population, suggesting a small population of oligometastatic and indolent cancers exist for each cancer type.
Keywords
brain metastasis, prolonged survival, neurologic death
Published Open-Access
yes
Recommended Citation
Pearce, Jane B; Hsu, Fang-Chi; Lanier, Claire M; et al., "Five-Year Survivors From Brain Metastases Treated With Stereotactic Radiosurgery: Biology, Improving Treatments, or Just Plain Luck?" (2023). Faculty, Staff and Student Publications. 1561.
https://digitalcommons.library.tmc.edu/uthgsbs_docs/1561
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