Differences between Acute Embolic and Atherosclerotic Middle Cerebral Artery Occlusion in Multiphase Arterial Spin-labeling Imaging

Authors

Yasuhiro Ito
Taku Sugiyama
Shunsuke Terasaka
Hitoshi Matsuzawa
Kuniaki Harada
Naoki Nakayama
Masaki Ito
Katsuhiko Maruichi
Miki Fujimura

Publication Date

5-15-2024

Journal

Neurologia medico-chirurgica

Abstract

Arterial spin-labeling magnetic resonance imaging (ASL-MRI) is widely used for evaluating collateral development in patients with acute ischemic stroke (AIS). This study aimed to characterize the findings of multiphase ASL-MRI between embolic and atherosclerotic large vessel occlusion (LVO) to aid in the differential diagnosis. Among 982 patients with AIS, 44 who were diagnosed with acute, symptomatic, and unilateral occlusion of the horizontal segment of the middle cerebral artery (MCA) were selected and categorized into embolic stroke (ES) and atherosclerosis (AT) groups. Using ASL-MRI (postlabeling delay [PLD] of 1.5, 2.0, and 2.5 s) at admission, the ipsilateral to contralateral ratio (ICR) of the signal intensity and its time-course increasing rate (from PLD 1.5 to 2.0 and 2.5, ΔICR) were measured and compared between the two groups. The mean ICR was significantly higher in the AT group than in the ES group (AT vs. ES: 0.49 vs. 0.27 for ICR

Keywords

Humans, Male, Female, Infarction, Middle Cerebral Artery, Aged, Spin Labels, Middle Aged, Magnetic Resonance Imaging, Diagnosis, Differential, Intracranial Arteriosclerosis, Aged, 80 and over, Embolic Stroke, Retrospective Studies

Comments

Supplementary Materials

PMID: 38432944