Dcis Knowledge of Women Choosing Between Active Surveillance and Surgery for Low-Risk DCIS

Authors

E G Engelhardt
R S J M Schmitz
M A Gerritsma
C M T Sondermeijer
E Verschuur
J H E Houtzager
R Griffioen
N Bijker
R M Mann
V Retèl
F H van Duijnhoven
J Wesseling
E M A Bleiker

Publication Date

10-1-2024

Journal

The Breast

Abstract

BACKGROUND: Ductal carcinoma in situ (DCIS) can progress to invasive breast cancer (IBC), but often never will. As we cannot predict accurately which DCIS-lesions will or will not progress to IBC, almost all women with DCIS undergo breast-conserving surgery supplemented with radiotherapy, or even mastectomy. In some countries, endocrine treatment is prescribed as well. This implies many women with non-progressive DCIS undergo overtreatment. To reduce this, the LORD patient preference trial (LORD-PPT) tests whether mammographic active surveillance (AS) is safe by giving women with low-risk DCIS a choice between treatment and AS. For this, sufficient knowledge about DCIS is crucial. Therefore, we assessed women's DCIS knowledge in association with socio-demographic and clinical characteristics.

METHODS: LORD-PPT participants (N = 376) completed a questionnaire assessing socio-demographic and clinical characteristics, risk perception, treatment choice and DCIS knowledge after being informed about their diagnosis and treatment options.

RESULTS: 66 % of participants had poor knowledge (i.e., answered ≤3 out of 7 knowledge items correctly). Most incorrect answers involved overestimating the safety of AS and misunderstanding of DCIS prognostic risks. Overall, women with higher DCIS knowledge score perceived their risk of developing IBC as being somewhat higher than women with poorer knowledge (p = 0.049). Women with better DCIS knowledge more often chose surgery whilst most women with poorer knowledge chose active surveillance (p = 0.049).

DISCUSSION: Our findings show that there is room for improvement of information provision to patients. Decision support tools for patients and clinicians could help to stimulate effective shared decision-making about DCIS management.

Keywords

Humans, Female, Carcinoma, Intraductal, Noninfiltrating, Breast Neoplasms, Middle Aged, Health Knowledge, Attitudes, Practice, Watchful Waiting, Adult, Surveys and Questionnaires, Mastectomy, Aged, Patient Preference, Mammography, Mastectomy, Segmental, Disease Progression, Choice Behavior

Comments

PMID: 38970983