Cannabinoids in Periodontology: Where Are We Now?

Authors

Yésica Carmona Rendón
Hernán Santiago Garzón
Bruno Bueno-Silva
Roger M Arce
Lina Janeth Suárez

Publication Date

11-30-2023

Journal

Antibiotics

Abstract

INTRODUCTION: Cannabinoids are a well-documented treatment modality for various immune and inflammatory diseases, including asthma, chronic obstructive pulmonary disease, Crohn's disease, arthritis, multiple sclerosis, and a range of neurodegenerative conditions. However, limited information is available regarding the therapeutic potential of cannabinoids in treating periodontal disease.

OBJECTIVE: The objective of this study is to analyze the current evidence on the antibacterial and immunomodulatory effects of cannabis and its role in the healing and regeneration processes within periodontal tissues.

RESULTS: This review discusses the potential role of cannabinoids in restoring periodontal tissue homeostasis.

CONCLUSIONS: The examination of the endocannabinoid system and the physiological effects of cannabinoids in the periodontium suggests that they possess immunomodulatory and antibacterial properties, which could potentially promote proper tissue healing and regeneration.

Keywords

cannabis, cannabinoids, periodontitis, regeneration

Comments

PMID: 38136721