Faculty, Staff and Student Publications
Publication Date
3-1-2024
Journal
Nature
Abstract
The fungus Candida albicans frequently colonizes the human gastrointestinal tract, from which it can disseminate to cause systemic disease. This polymorphic species can transition between growing as single-celled yeast and as multicellular hyphae to adapt to its environment. The current dogma of C. albicans commensalism is that the yeast form is optimal for gut colonization, whereas hyphal cells are detrimental to colonization but critical for virulence
Keywords
Animals, Female, Humans, Male, Mice, Bacteria, Candida albicans, Fungal Proteins, Gastrointestinal Microbiome, Hyphae, Immunoglobulin A, Intestines, Mycotoxins, Symbiosis, Virulence
Included in
Bioinformatics Commons, Biomedical Informatics Commons, Medical Sciences Commons, Oncology Commons
Comments
Supplementary Materials
Data Availability Statement
PMID: 38448595