Coating Formulation Change Leads to Inferior Performance of Long-Lasting Insecticidal Nets in Papua New Guinea

Authors

Nakei Bubun
Evodia Anetul
Melanie Koinari
Timothy W Freeman
Stephan Karl

Publication Date

11-24-2022

Journal

Cancer Medicine

Abstract

BACKGROUND: Long-lasting insecticidal nets (LLINs) play a key role in reducing malaria transmission in endemic countries. In a previous study, the authors demonstrated a substantial decrease in the bioefficacy of LLINs for malaria prevention delivered to Papua New Guinea (PNG) between 2013 and 2019. This coincided with a rise in malaria cases in the country. The present study was aimed at determining the underlying cause of the reduced bioefficacy observed in these LLINs. The main hypothesis was that a change in the coating formulation of the respective LLIN product was responsible, and had led to significantly altered product properties and performance.

METHODS: A set of PermaNet

RESULTS: High polymer fluorine content (average 3.2 g/kg) was measured in PermaNet

CONCLUSION: A change in coating formulation of PermaNet

Keywords

Animals, Insecticides, Papua New Guinea, Fluorine, Culicidae, Fluorocarbons, Polymers, cancer, clinical management, hereditary, variant of uncertain significance, variant reclassification

Comments

Supplementary Material

Data Availability Statement

PMID: 36426404

DOI

10.1002/cam4.5202

PMID

36426404

PMCID

PMC9939195

PubMedCentral® Posted Date

November 2022

PubMedCentral® Full Text Version

Post-print

Published Open-Access

yes