Translating Energy Balance Research From the Bench to the Clinic to the Community: Parallel Animal-Human Studies in Cancer

Authors

Miriam B Garcia
Keri L Schadler
Joya Chandra
Steven K Clinton
Kerry S Courneya
Zobeida Cruz-Monserrate
Carrie R Daniel
Andrew J Dannenberg
Wendy Demark-Wahnefried
Mark W Dewhirst
Carol J Fabian
Stephen D Hursting
Melinda L Irwin
Neil M Iyengar
Jennifer L McQuade
Kathryn H Schmitz
Karen Basen-Engquist

Publication Date

1-1-2023

Journal

CA: A Cancer Journal for Clinicians

Abstract

Advances in energy balance and cancer research to date have largely occurred in siloed work in rodents or patients. However, substantial benefit can be derived from parallel studies in which animal models inform the design of clinical and population studies or in which clinical observations become the basis for animal studies. The conference Translating Energy Balance from Bench to Communities: Application of Parallel Animal-Human Studies in Cancer, held in July 2021, convened investigators from basic, translational/clinical, and population science research to share knowledge, examples of successful parallel studies, and strong research to move the field of energy balance and cancer toward practice changes. This review summarizes key topics discussed to advance research on the role of energy balance, including physical activity, body composition, and dietary intake, on cancer development, cancer outcomes, and healthy survivorship.

Keywords

Animals, Humans, Neoplasms, Exercise, body composition, cancer, cancer survivorship, diet, exercise, nutrition, translational research

Comments

PMID: 36825928