Management of Anhedonia After Epilepsy Surgery

Authors

Gerardo Maria de Araujo Filho
Antonio L Teixeira

Publication Date

1-1-2024

Journal

Epilepsy & Behavior Reports

Abstract

Anhedonia is clinically defined as difficulty or inability to feel pleasure or to be motivated to perform activities that were previously pleasurable. Anhedonia is a core feature of depressive disorders but can be present in other conditions such as substance use and anxiety disorders. Herein we report the case of a 34-year-old female who developed marked anhedonia after left cortico-amygdalohippocampectomy. Despite optimal seizure control, the person struggled with anhedonia and other depressive symptoms. After ruling out medico-neurologic complications, she was prescribed with a selective serotonin reuptake inhibitor and cognitive-behavioral therapy. Anhedonia can be a challenging neuropsychiatric presentation that requires ruling out the effects of antiseizure medications, neurosurgery, and other drugs before prescribing antidepressants.

Keywords

Anhedonia, Depression, Epilepsy Surgery, Selective Serotonin Reuptake Inhibitor, Temporal Lobe Epilepsy

Comments

PMID: 38495401

DOI

10.1016/j.ebr.2024.100658

PMID

38495401

PMCID

PMC10940138

PubMedCentral® Posted Date

March 2024

PubMedCentral® Full Text Version

Post-print

Published Open-Access

yes