Faculty, Staff and Student Publications
Publication Date
5-16-2023
Journal
Cell Reports Medicine
DOI
10.1016/j.xcrm.2023.101039
PMID
37196631
PMCID
PMC10213830
PubMedCentral® Posted Date
May 2023
PubMedCentral® Full Text Version
Post-print
Abstract
Tintelnot et al. identified enrichment of indole-3-acetic acid (3-IAA), a tryptophan metabolite produced by gut microbiota, as a predictor of chemotherapy response in pancreatic adenocarcinoma. Recapitulated in mouse models, 3-IAA represents a novel potential therapeutic approach for chemotherapy sensitization.
Keywords
Animals, Mice, Adenocarcinoma, Pancreatic Neoplasms, Bacteria
Published Open-Access
yes
Recommended Citation
Y David Seo and Jennifer A Wargo, "From Bugs to Drugs: Bacterial 3-Iaa Enhances Efficacy of Chemotherapy in Pancreatic Cancer" (2023). Faculty, Staff and Student Publications. 2313.
https://digitalcommons.library.tmc.edu/uthgsbs_docs/2313
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