Faculty, Staff and Student Publications
Publication Date
5-16-2023
Journal
Cell Reports Medicine
Abstract
Tintelnot et al. identified enrichment of indole-3-acetic acid (3-IAA), a tryptophan metabolite produced by gut microbiota, as a predictor of chemotherapy response in pancreatic adenocarcinoma. Recapitulated in mouse models, 3-IAA represents a novel potential therapeutic approach for chemotherapy sensitization.
Keywords
Animals, Mice, Adenocarcinoma, Pancreatic Neoplasms, Bacteria
DOI
10.1016/j.xcrm.2023.101039
PMID
37196631
PMCID
PMC10213830
PubMedCentral® Posted Date
May 2023
PubMedCentral® Full Text Version
Post-print
Published Open-Access
yes
Included in
Bioinformatics Commons, Biological Phenomena, Cell Phenomena, and Immunity Commons, Biomedical Informatics Commons, Medical Cell Biology Commons, Oncology Commons
Comments
PMID: 37196631