Faculty, Staff and Student Publications

Publication Date

5-16-2023

Journal

Cell Reports Medicine

Abstract

Tintelnot et al. identified enrichment of indole-3-acetic acid (3-IAA), a tryptophan metabolite produced by gut microbiota, as a predictor of chemotherapy response in pancreatic adenocarcinoma. Recapitulated in mouse models, 3-IAA represents a novel potential therapeutic approach for chemotherapy sensitization.

Keywords

Animals, Mice, Adenocarcinoma, Pancreatic Neoplasms, Bacteria

Comments

PMID: 37196631

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