Visuo-Frontal Interactions During Social Learning in Freely Moving Macaques

Authors

Melissa Franch
Sudha Yellapantula
Arun Parajuli
Natasha Kharas
Anthony Wright
Behnaam Aazhang
Valentin Dragoi

Publication Date

3-1-2024

Journal

Nature

Abstract

Social interactions represent a ubiquitous aspect of our everyday life that we acquire by interpreting and responding to visual cues from conspecifics1. However, despite the general acceptance of this view, how visual information is used to guide the decision to cooperate is unknown. Here, we wirelessly recorded the spiking activity of populations of neurons in the visual and prefrontal cortex in conjunction with wireless recordings of oculomotor events while freely moving macaques engaged in social cooperation. As animals learned to cooperate, visual and executive areas refined the representation of social variables, such as the conspecific or reward, by distributing socially relevant information among neurons in each area. Decoding population activity showed that viewing social cues influences the decision to cooperate. Learning social events increased coordinated spiking between visual and prefrontal cortical neurons, which was associated with improved accuracy of neural populations to encode social cues and the decision to cooperate. These results indicate that the visual-frontal cortical network prioritizes relevant sensory information to facilitate learning social interactions while freely moving macaques interact in a naturalistic environment.

Keywords

Animals, Action Potentials, Cooperative Behavior, Cues, Decision Making, Executive Function, Macaca, Neurons, Photic Stimulation, Prefrontal Cortex, Reward, Social Learning, Visual Cortex, Wireless Technology, Cooperation, Neural circuits, Extrastriate cortex, Social behaviour

Comments

This article has been corrected. See Nature. 2024 Mar 22;628(8008):E3.

Associated Data

PMID: 38355804