The Challenges and Opportunities of scRNA-Seq in COVID-19 Research and Clinical Translation

Authors

Wendao Liu
Xiaohua Ye
Zhiqiang An
Zhongming Zhao

Publication Date

12-15-2022

Journal

Virology Journal

Abstract

The application of single-cell RNA sequencing in COVID-19 research has greatly improved our understanding of COVID-19 pathogenesis and immunological characteristics. In this commentary, we discuss the current challenges, limitations, and perspectives in harnessing the power of single-cell RNA sequencing to accelerate both basic research and therapeutic development for COVID-19 and other emerging infectious diseases.

Keywords

Humans, COVID-19, Single-Cell Analysis, Single-Cell Gene Expression Analysis, Sequence Analysis, RNA/, COVID-19, SARS-CoV-2, Single-cell RNA sequencing, COVID-19 sequela, Single-cell VDJ sequencing

Comments

Associated Data

PMID: 36522785