Gene Promoters Are Genomically Encoded To Facilitate Histone Exchange/Incorporation

Authors

Blaine Bartholomew

Publication Date

5-1-2025

Journal

PLoS Biology

DOI

10.1371/journal.pbio.3003160

PMID

40359406

PMCID

PMC12074589

PubMedCentral® Posted Date

5-13-2025

PubMedCentral® Full Text Version

Post-print

Abstract

Gene promoters are intrinsically hardwired not only to facilitate transcription preinitiation complex formation but also the release of paused RNA polymerase by H2A.Z. A new PLOS Biology study reveals poly (dA) tracts at promoters positively stimulate H2A.Z incorporation by the SWR complex in yeast.

Keywords

Histones, Promoter Regions, Genetic, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, Transcription, Genetic, DNA-Directed RNA Polymerases

Published Open-Access

yes

Recommended Citation

Blaine Bartholomew, "Gene Promoters Are Genomically Encoded To Facilitate Histone Exchange/Incorporation" (2025). Faculty, Staff and Student Publications. 2566.
https://digitalcommons.library.tmc.edu/uthgsbs_docs/2566