Faculty, Staff and Student Publications
Publication Date
1-1-2025
Journal
Leukemia Research Reports
DOI
10.1016/j.lrr.2024.100485
PMID
39691506
PMCID
PMC11647623
PubMedCentral® Posted Date
11-28-2024
PubMedCentral® Full Text Version
Post-print
Abstract
Delayed hemolytic transfusion reaction (DHTR) poses a significant challenge in patients receiving blood transfusions. This case report highlights the complexities of managing DHTR in a newly diagnosed chronic myelomonocytic leukemia (CMML) patient with clinically significant JKa and little c antibodies during induction chemotherapy. A 46-year-old woman with CMML-2 who presented for induction chemotherapy was found to have hemolytic anemia. Due to presence of JKa and little c antibodies, she required intensive monitoring and supportive care measures. The coexistence of JKa and little c antibodies complicates transfusion management and chemotherapy tolerance in CMML patients.
Keywords
Hemolytic transfusion reactions, CMML, Induction therapy
Published Open-Access
yes
Recommended Citation
Park, Grace S; Atluri, Himachandana; DiNardo, Courtney D; et al., "Management of Hemolytic Transfusion Reactions in a Patient With Chronic Myelomonocytic Leukemia and Rare Antibodies: A Case Report" (2025). Faculty, Staff and Student Publications. 2985.
https://digitalcommons.library.tmc.edu/uthgsbs_docs/2985
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