Publication Date

1-1-2023

Journal

Leukemia Research Report

Abstract

Membranous nephropathy (MN) is an uncommon renal presentation in patients with chronic lymphocytic leukemia (CLL), and as such, there is no standard therapy for these patients. A few cases of MN in CLL have been described with varying success in MN treatment involving alkylating agents and fludarabine. Here we report the first case of MN in a patient with CLL treated with ibrutinib with complete renal response. This presentation underlines the importance of recognizing rare glomerular diseases that may occur with CLL and offers a new therapeutic avenue to the treatment of CLL-associated MN.

Keywords

Case report, Membranous nephropathy, Chronic lymphocytic leukemia, Bruton tyrosine kinase, Paraneoplastic

Comments

PMID: 37457553

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