Publication Date
3-7-2024
Journal
The Journal of Headache and Pain
Abstract
BACKGROUND: New guidelines for cluster headache clinical trials were recently published. We welcome these new guidelines and raise additional considerations in trial methodologies.
MAIN BODY: We present non-inferiority trials to overcome ethical issues with placebo use, and additionally discuss issues with trial recruitment.
CONCLUSIONS: We highlight some possible issues and solutions to be considered with the recently published cluster headache trial guidelines.
Keywords
Humans, Clinical Trials as Topic, Cluster Headache, Equivalence Trials as Topic
Included in
Bioinformatics Commons, Biomedical Informatics Commons, Medical Sciences Commons, Oncology Commons, Pain Management Commons
Comments
PMID: 38454380