Optimal Size and Peg Coating of Gold Nanoparticles for Prolonged Blood Circulation: A Statistical Analysis of Published Data

Authors

Dmitry Nevozhay
Ronald Rauch
Zhongya Wang
Konstantin V Sokolov

Publication Date

1-28-2025

Journal

Nanoscale Advances

DOI

10.1039/d4na00782d

PMID

39811023

PMCID

PMC11726233

PubMedCentral® Posted Date

1-13-2025

PubMedCentral® Full Text Version

Post-print

Abstract

This study presents a statistical analysis of how gold nanoparticle (GNP) size and polyethylene glycol (PEG) coating molecular weight (MW) affect the circulation of nanoparticles in blood. We showed a non-linear relationship with interaction between GNP size and PEG MW. The findings revealed a threshold effect, and recommendations for GNP coating are discussed.

Published Open-Access

yes

Recommended Citation

Nevozhay, Dmitry; Rauch, Ronald; Wang, Zhongya; et al., "Optimal Size and Peg Coating of Gold Nanoparticles for Prolonged Blood Circulation: A Statistical Analysis of Published Data" (2025). Faculty, Staff and Student Publications. 3839.
https://digitalcommons.library.tmc.edu/uthgsbs_docs/3839