The New World of RNA Diagnostics and Therapeutics

Authors

Giovanni Blandino
Roberto Dinami
Marco Marcia
Eleni Anastasiadou
Brid M Ryan
Alina Catalina Palcau
Luigi Fattore
Giulia Regazzo
Rosanna Sestito
Rossella Loria
Ana Belén Díaz Méndez
Maria Chiara Cappelletto
Claudio Pulito
Laura Monteonofrio
George A Calin
Gabriella Sozzi
Jit Kong Cheong
Ranit Aharonov
Gennaro Ciliberto

Publication Date

7-29-2023

Journal

Journal of Experimental & Clinical Cancer Research

Abstract

The 5th Workshop IRE on Translational Oncology was held in Rome (Italy) on 27-28 March at the IRCCS Regina Elena National Cancer Institute. This meeting entitled "The New World of RNA diagnostics and therapeutics" highlightes the significant progress in the RNA field made over the last years. Research moved from pure discovery towards the development of diagnostic biomarkers or RNA-base targeted therapies seeking validation in several clinical trials. Non-coding RNAs in particular have been the focus of this workshop due to their unique properties that make them attractive tools for the diagnosis and therapy of cancer.This report collected the presentations of many scientists from different institutions that discussed recent oncology research providing an excellent overview and representative examples for each possible application of RNA as biomarker, for therapy or to increase the number of patients that can benefit from precision oncology treatment.In particular, the meeting specifically emphasized two key features of RNA applications: RNA diagnostic (Blandino, Palcau, Sestito, Díaz Méndez, Cappelletto, Pulito, Monteonofrio, Calin, Sozzi, Cheong) and RNA therapeutics (Dinami, Marcia, Anastasiadou, Ryan, Fattore, Regazzo, Loria, Aharonov).

Keywords

Humans, Neoplasms, Precision Medicine, Biomarkers, Medical Oncology, Italy

Comments

PMID: 37507791