Faculty, Staff and Student Publications

Publication Date

10-5-2022

Journal

Cancer Discovery

DOI

10.1158/2159-8290.CD-22-0829

PMID

36196575

PMCID

PMC12123373

PubMedCentral® Posted Date

5-30-2025

PubMedCentral® Full Text Version

Author MSS

Abstract

Perineural spread is an ominous feature of cancer. Here, Deborde and colleagues describe for the first time the biophysical coupling driving this route of tumor spread and the role of Schwann cell activation in the mobilization of cancer cells within and along the tumor-associated nerves. See related article by Deborde et al., p. 2454 (8).

Keywords

Humans, Pancreatic Neoplasms, Schwann Cells

Published Open-Access

yes

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