Dual Targeting of EZH2 and EZH1 Drives Exit of Leukemia Stem Cells From Quiescence and Potentiates Chemotherapy in Acute Myeloid Leukemia

Authors

Hiroki Akiyama
Yuki Nishida
Kyung Hee Chang
Andrea D Bedoy
Muharrem Muftuoglu
Wencai Ma
Mahesh Basyal
Zoe Hirschi
Daisuke Honma
Shinji Tsutsumi
Jing Wang
Weiguo Zhang
Xuelin Huang
Raajit K Rampal
Olalekan O Oluwole
Dale Lee Bixby
Naval G Daver
Michael Andreeff

Publication Date

4-24-2025

Journal

Blood Cancer Journal

DOI

10.1038/s41408-025-01266-0

PMID

40274779

PMCID

PMC12022017

PubMedCentral® Posted Date

4-24-2025

PubMedCentral® Full Text Version

Post-print

Published Open-Access

yes

Recommended Citation

Akiyama, Hiroki; Nishida, Yuki; Chang, Kyung Hee; et al., "Dual Targeting of EZH2 and EZH1 Drives Exit of Leukemia Stem Cells From Quiescence and Potentiates Chemotherapy in Acute Myeloid Leukemia" (2025). Faculty, Staff and Student Publications. 4513.
https://digitalcommons.library.tmc.edu/uthgsbs_docs/4513