American Radium Society (ARS) Appropriate Use Criteria (AUC) for Extrahepatic Cholangiocarcinoma

Authors

Leila T Tchelebi
Krishan R Jethwa
Anna T Levy
Christopher J Anker
Timothy Kennedy
Elliot Grodstein
Christopher L Hallemeier
Salma K Jabbour
Ed Kim
Rachit Kumar
Percy Lee
William Small
Vonetta M Williams
Navesh Sharma
Suzanne Russo

Publication Date

2-1-2023

Journal

American Journal of Clinical Oncology

DOI

10.1097/COC.0000000000000969

PMID

36534388

PMCID

PMC9855763

PubMedCentral® Posted Date

12-19-2022

PubMedCentral® Full Text Version

Post-print

Abstract

Although uncommon, extrahepatic cholangiocarcinoma (EHCC) is a deadly malignancy, and the treatment approaches remain controversial. While surgery remains the only cure, few patients are candidates for resection up front, and there are high rates of both local and distant failure following resection. Herein, we systematically review the available evidence regarding treatment approaches for patients with EHCC, including surgery, radiation, and chemotherapy. The evidence regarding treatment outcomes was assessed using the Population, Intervention, Comparator, Outcome, and Study design (PICOS) framework. A summary of recommendations based on the available literature is outlined for specific clinical scenarios encountered by providers in the clinic to guide the management of these patients.

Keywords

Humans, United States, Radium, Area Under Curve, Cholangiocarcinoma, Bile Duct Neoplasms, Bile Ducts, Intrahepatic, Extrahepatic cholangiocarcinoma, radiation therapy, chemotherapy, surgery, liver transplant

Published Open-Access

yes

Recommended Citation

Tchelebi, Leila T; Jethwa, Krishan R; Levy, Anna T; et al., "American Radium Society (ARS) Appropriate Use Criteria (AUC) for Extrahepatic Cholangiocarcinoma" (2023). Faculty, Staff and Student Publications. 4578.
https://digitalcommons.library.tmc.edu/uthgsbs_docs/4578