Current Treatment Strategies and Risk Stratification for Oral Carcinoma

Authors

Issa Mohamad
Mica D E Glaun
Kumar Prabhash
Ahmed Busheri
Stephen Y Lai
Vanita Noronha
Ali Hosni

Publication Date

5-1-2023

Journal

American Society of Clinical Oncology Educational Book

DOI

10.1200/EDBK_389810

PMID

37200591

Abstract

Management of oral cavity squamous cell carcinoma (OSCC) involves a multidisciplinary team approach. Surgery is ideally the primary treatment option for nonmetastatic OSCC, and less invasive curative surgical approaches are preferred in early-stage disease to minimize surgical-related morbidity. For patients at high risk of recurrence, adjuvant treatment using radiation therapy or chemoradiation is often used. Systemic therapy may also be used in the neoadjuvant setting (for advanced-stage disease with the intent of mandibular preservation) or in the palliative setting (for nonsalvageable locoregional recurrence and/or distant metastases). Patient involvement in treatment decision is the key for patient-driven management, particularly in clinical situation with poor prognosis, for example, early postoperative recurrence before planned adjuvant therapy.

Keywords

Humans, Neoplasm Recurrence, Local, Mouth Neoplasms, Combined Modality Therapy, Carcinoma, Squamous Cell, Risk Assessment, Neoplasm Staging, Retrospective Studies

Published Open-Access

yes

Recommended Citation

Mohamad, Issa; Glaun, Mica D E; Prabhash, Kumar; et al., "Current Treatment Strategies and Risk Stratification for Oral Carcinoma" (2023). Faculty, Staff and Student Publications. 4668.
https://digitalcommons.library.tmc.edu/uthgsbs_docs/4668