Faculty, Staff and Student Publications
Publication Date
12-11-2023
Journal
Acta Dermato-Venereologica
Abstract
Metformin is a widely used drug for treatment of diabetes mellitus, due to its safety and efficacy. In addition to its role as an antidiabetic drug, numerous beneficial effects of metformin have enabled its use in various diseases. Considering the anti-androgenic, anti-angiogenic, anti-fibrotic and antioxidant properties of metformin, it may have the potential to improve chronic inflammatory skin diseases. However, further evidence is needed to confirm the efficacy of metformin in dermatological conditions, This review focuses on exploring the therapeutic targets of metformin in acne vulgaris, hidradenitis suppurativa and rosacea, by studying their pathogeneses.
Keywords
Humans, Hidradenitis Suppurativa, Metformin, Acne Vulgaris, Rosacea, Skin
DOI
10.2340/actadv.v103.18392
PMID
38078688
PMCID
PMC10726377
PubMedCentral® Posted Date
December 2023
PubMedCentral® Full Text Version
Post-print
Published Open-Access
yes
Included in
Bioinformatics Commons, Biomedical Informatics Commons, Dermatology Commons, Medical Sciences Commons, Skin and Connective Tissue Diseases Commons