Faculty, Staff and Student Publications
Publication Date
12-1-2022
Journal
Cell Reprogramming
DOI
10.1089/cell.2022.0128
PMID
36409720
PMCID
PMC9805845
PubMedCentral® Posted Date
12-12-2022
PubMedCentral® Full Text Version
Post-print
Abstract
By dissecting and comparing the transcriptional trajectories and epigenomic traits of reprogramming and transforming cells at the single-cell resolution, Huyghe et al discovered Bcl11b and Atoh8, two key transcription factors controlling cell plasticity during pluripotent reprogramming and oncogenic transformation.
Keywords
Humans, Cell Plasticity, Transcription Factors, Cell Transformation, Neoplastic, Tumor Suppressor Proteins, Cellular Reprogramming, Repressor Proteins, cellular plasticity, reprogramming, transformation, single-cell
Published Open-Access
yes
Recommended Citation
Mo-Fan Huang, Rachel Shoemaker, and Dung-Fang Lee, "Bcl11b and Atoh8 Coordinate Cellular Plasticity for Reprogramming and Transformation" (2022). Faculty, Staff and Student Publications. 4686.
https://digitalcommons.library.tmc.edu/uthgsbs_docs/4686
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