Editorial: Updates on Radiation-Induced Lymphopenia

Authors

Pim J J Damen
Steven H Lin
Peter S N van Rossum

Publication Date

1-1-2024

Journal

Frontiers in Oncology

DOI

10.3389/fonc.2024.1448658

PMID

39015501

PMCID

PMC11249733

PubMedCentral® Posted Date

7-2-2024

PubMedCentral® Full Text Version

Post-print

Abstract

Radiotherapy is a commonly employed and effective treatment for cancer, seeking to achieve an optimal balance between tumor cell death and minimizing damage to healthy tissues. Radiation-induced lymphopenia (RIL) is a common side effect due to the high radiosensitivity of lymphocytes even at low doses (< 1Gy), leading to their direct depletion (1). While the detrimental effects of radiotherapy on lymphocytes have been recognized since 1905, its influence on tumor control and survival has remained largely unclear until recently (2). Moreover, awareness and understanding of the prognostic effects of RIL remain limited in daily clinical practice.

Published Open-Access

yes

Recommended Citation

Pim J J Damen, Steven H Lin, and Peter S N van Rossum, "Editorial: Updates on Radiation-Induced Lymphopenia" (2024). Faculty, Staff and Student Publications. 4744.
https://digitalcommons.library.tmc.edu/uthgsbs_docs/4744