Faculty, Staff and Student Publications
Publication Date
9-1-2022
Journal
Nature Medicine
DOI
10.1038/s41591-022-01998-7
PMID
36109644
PMCID
PMC12036812
PubMedCentral® Posted Date
4-28-2025
PubMedCentral® Full Text Version
Author MSS
Abstract
Using comprehensive single-cell profiling, two studies reveal the molecular phenotypes of CAR T cells associated with durable response in patients with lymphoma, and highlight the role of CAR regulatory T cells in mediating resistance.
Keywords
Drug Resistance, Neoplasm, Receptors, Chimeric Antigen, T-Lymphocytes, Regulatory
Published Open-Access
yes
Recommended Citation
Neeraj Saini and Sattva S Neelapu, "CAR Treg Cells: Prime Suspects in Therapeutic Resistance" (2022). Faculty, Staff and Student Publications. 4887.
https://digitalcommons.library.tmc.edu/uthgsbs_docs/4887
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