Faculty, Staff and Student Publications

Publication Date

1-8-2024

Journal

American Journal of Hematology

DOI

10.1016/j.ccell.2023.12.009

PMID

38194911

Abstract

Neoadjuvant chemotherapy plus immunotherapy for triple-negative breast cancer (TNBC) is associated with improved but incomplete response. In this issue of Cancer Cell, Shiao et al. characterize longitudinal biopsies from a window of opportunity study with single-cell RNA sequencing (scRNA-seq) and spatial proteomic profiling and elucidate synergy between radiotherapy (RT) and pembrolizumab.

Keywords

Humans, Radioimmunotherapy, Triple Negative Breast Neoplasms, Neoadjuvant Therapy, Patient Selection, Proteomics, Tumor Microenvironment

Published Open-Access

yes

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