Faculty, Staff and Student Publications
Publication Date
1-23-2024
Journal
Translational Psychiatry
DOI
10.1038/s41398-023-02723-9
PMID
38263400
PMCID
PMC10806086
PubMedCentral® Posted Date
1-23-2024
PubMedCentral® Full Text Version
Post-print
Abstract
Background: Suicide is the second leading cause of death for adolescents in the United States. However, relatively little is known about the forms of atypical neuro-cognitive function that are correlates of suicidal ideation (SI). One form of cognitive/affective function that, when dysfunctional, is associated with SI is emotion regulation. However, very little work has investigated the neural correlates of emotion dysregulation in adolescents with SI.
Methods: Participants (N = 111 aged 12-18, 32 females, 31 [27.9%] reporting SI) were recruited shortly after their arrival at a residential care facility where they had been referred for behavioral and mental health problems. Daily reports of SI were collected during the participants' first 90-days in residential care. Participants were presented with a task-fMRI measure of emotion regulation - the Affective Number Stroop task shortly after recruitment. Participants were divided into two groups matched for age, sex and IQ based on whether they demonstrated SI.
Results: Participants who demonstrated SI showed increased recruitment of regions including dorsomedial prefrontal cortex/supplemental motor area and parietal cortex during task (congruent and incongruent) relative to view trials in the context of emotional relative to neutral distracters.
Conclusions: Participants with SI showed increased recruitment of regions implicated in executive control during the performance of a task indexing automatic emotion regulation. Such data might suggest a relative inefficiency in the recruitment of these regions in individuals with SI.
Keywords
Female, Humans, Adolescent, Suicidal Ideation, Emotional Regulation, Suicide, Emotions, Executive Function, Predictive markers, Human behaviour
Published Open-Access
yes
Recommended Citation
Dobbertin, Matthew; Blair, Karina S; Aloi, Joseph; et al., "Neural Correlates of Automatic Emotion Regulation and Their Association With Suicidal Ideation in Adolescents During the First 90-Days of Residential Care" (2024). Faculty, Staff and Student Publications. 5203.
https://digitalcommons.library.tmc.edu/uthgsbs_docs/5203
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Comments
This article has been corrected. See Transl Psychiatry. 2024 Feb 19;14:100.