Inhibition of Menin, BCL-2, and FLT3 Combined With a Hypomethylating Agent Cures NPM1/FLT3-Itd/-Tkd Mutant Acute Myeloid Leukemia in a Patient-Derived Xenograft Model

Authors

Bing Z Carter
Po Yee Mak
Wenjing Tao
Lauren B Ostermann
Duncan H Mak
Baozhen Ke
Peter Ordentlich
Gerard M McGeehan
Michael Andreeff

Language

English

Publication Date

9-1-2023

Journal

Haematologica

DOI

10.3324/haematol.2022.281927

PMID

36727398

PMCID

PMC10483344

PubMedCentral® Full Text Version

Post-print

Keywords

Humans, fms-Like Tyrosine Kinase 3, Heterografts, Leukemia, Myeloid, Acute, Mutation, Nuclear Proteins, Proto-Oncogene Proteins c-bcl-2, Animals, Mice

Published Open-Access

yes

Recommended Citation

Carter, Bing Z; Mak, Po Yee; Tao, Wenjing; et al., "Inhibition of Menin, BCL-2, and FLT3 Combined With a Hypomethylating Agent Cures NPM1/FLT3-Itd/-Tkd Mutant Acute Myeloid Leukemia in a Patient-Derived Xenograft Model" (2023). Faculty, Staff and Student Publications. 5283.
https://digitalcommons.library.tmc.edu/uthgsbs_docs/5283