NMR-Based Metabolomic Profiling for Brain Cancer Diagnosis and Treatment Guidance

Authors

Julia R Zickus
José S Enriquez
Paytience Smith
Bill T Sun
Muxin Wang
Aldo Morales
Pratip K Bhattacharya
Shivanand Pudakalakatti

Language

English

Publication Date

9-11-2025

Journal

Metabolites

DOI

10.3390/metabo15090607

PMID

41002991

PMCID

PMC12472021

PubMedCentral® Posted Date

9-11-2025

PubMedCentral® Full Text Version

Post-print

Abstract

Nuclear magnetic resonance (NMR) spectroscopy is a routinely used analytical tool for studying chemical entities of varying molecular sizes, ranging from approximately 20 Da to ~45 kDa, and in some cases even larger. Over the past two decades, the use of NMR spectroscopy has significantly expanded to the study of metabolomics. In this medium-sized review, the application of NMR-based metabolomics in the diagnosis, therapeutic intervention, and guidance of therapy for various types of brain cancer is discussed.

Keywords

NMR spectroscopy, brain cancer, metabolomics, diagnosis, therapeutic intervention

Published Open-Access

yes

Recommended Citation

Zickus, Julia R; Enriquez, José S; Smith, Paytience; et al., "NMR-Based Metabolomic Profiling for Brain Cancer Diagnosis and Treatment Guidance" (2025). Faculty, Staff and Student Publications. 5357.
https://digitalcommons.library.tmc.edu/uthgsbs_docs/5357