50-nm Gas-Filled Protein Nanostructures to Enable the Access of Lymphatic Cells by Ultrasound Technologies

Authors

Qionghua Shen
Zongru Li
Yixian Wang
Matthew D Meyer
Marc T De Guzman
Janie C Lim
Han Xiao
Richard R Bouchard
George J Lu

Language

English

Publication Date

7-1-2024

Journal

Advanced Materials - Wiley Online Library

DOI

10.1002/adma.202307123

PMID

38533973

PMCID

PMC11550859

PubMedCentral® Posted Date

7-1-2025

PubMedCentral® Full Text Version

Author MSS

Abstract

Ultrasound imaging and ultrasound-mediated gene and drug delivery are rapidly advancing diagnostic and therapeutic methods; however, their use is often limited by the need for microbubbles, which cannot transverse many biological barriers due to their large size. Here, the authors introduce 50-nm gas-filled protein nanostructures derived from genetically engineered gas vesicles(GVs) that are referred to as

Keywords

Animals, Nanostructures, Mice, Microbubbles, Lymph Nodes, Gases, Ultrasonography, Proteins, gas vesicles, lymph nodes, nanobubbles, protein nanostructures, ultrasound

Published Open-Access

yes

Recommended Citation

Shen, Qionghua; Li, Zongru; Wang, Yixian; et al., "50-nm Gas-Filled Protein Nanostructures to Enable the Access of Lymphatic Cells by Ultrasound Technologies" (2024). Faculty, Staff and Student Publications. 5369.
https://digitalcommons.library.tmc.edu/uthgsbs_docs/5369