Faculty, Staff and Student Publications
Language
English
Publication Date
9-19-2025
Journal
iScience
DOI
10.1016/j.isci.2025.113334
PMID
40917877
PMCID
PMC12410359
PubMedCentral® Posted Date
8-11-2025
PubMedCentral® Full Text Version
Post-print
Abstract
Efforts to efficiently target brain tumors are constrained by the dearth of appropriate models to study tumor behavior toward treatment approaches as well as potential side effects to the surrounding normal tissue. We established a reproducible cerebral organoid model of brain tumorigenesis in an autologous setting by overexpressing
Keywords
Developmental neuroscience, Cancer, Experimental models in systems biology
Published Open-Access
yes
Recommended Citation
Schickel, Esther; Bender, Tamara; Kaysan, Leon; et al., "Human Cerebral Organoids Model Tumor Initiation and Infiltration in an Autologous Astrocyte-Supported Setting" (2025). Faculty, Staff and Student Publications. 5783.
https://digitalcommons.library.tmc.edu/uthgsbs_docs/5783
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