Faculty, Staff and Student Publications

Language

English

Publication Date

8-1-2025

Journal

Nature Cancer

DOI

10.1038/s43018-025-01025-x

PMID

40775548

PMCID

PMC12412309

PubMedCentral® Posted Date

9-6-2025

PubMedCentral® Full Text Version

Author MSS

Abstract

Although the first generation of cancer immunotherapeutics produced unprecedented improvements in clinical outcomes for individuals with cancer, novel strategies to increase treatment specificity, delivery efficiency and pharmacokinetics are still needed. In this Review, we describe the potential advantages and current limitations of nanomaterials for cancer immunotherapy and highlight rational uses of nanosystems to generate potent and durable antitumor immune responses. We close with a review of the current state of clinical development of nanomedicine for cancer immunotherapy.

Keywords

Humans, Neoplasms, Immunotherapy, Nanomedicine, Nanotechnology, Medical Oncology, Animals, Nanostructures, Nanoparticles

Published Open-Access

yes

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