Faculty, Staff and Student Publications

Authors

Rick W Wright
Laura J Huston
Amanda K Haas
Jacquelyn S Pennings
Christina R Allen
Daniel E Cooper
Thomas M DeBerardino
Warren R Dunn
Brett Brick A Lantz
Kurt P Spindler
Michael J Stuart
John P Albright
Annunziato Ned Amendola
Jack T Andrish
Christopher C Annunziata
Robert A Arciero
Bernard R Bach
Champ L Baker
Arthur R Bartolozzi
Keith M Baumgarten
Jeffery R Bechler
Jeffrey H Berg
Geoffrey A Bernas
Stephen F Brockmeier
Robert H Brophy
Charles A Bush-Joseph
J Brad Butler
John D Campbell
James L Carey
James E Carpenter
Brian J Cole
Jonathan M Cooper
Charles L Cox
R Alexander Creighton
Diane L Dahm
Tal S David
David C Flanigan
Robert W Frederick
Theodore J Ganley
Elizabeth A Garofoli
Charles J Gatt
Steven R Gecha
James Robert Giffin
Sharon L Hame
Jo A Hannafin
Christopher D Harner
Norman Lindsay Harris
Keith S Hechtman
Elliott B Hershman
Rudolf G Hoellrich
David C Johnson
Timothy S Johnson
Morgan H Jones
Christopher C Kaeding
Ganesh V Kamath
Thomas E Klootwyk
Bruce A Levy
C Benjamin Ma
G Peter Maiers
Robert G Marx
Matthew J Matava
Gregory M Mathien
David R McAllister
Eric C McCarty
Robert G McCormack
Bruce S Miller
Carl W Nissen
Daniel F O'Neill
Brett D Owens
Richard D Parker
Mark L Purnell
Arun J Ramappa
Michael A Rauh
Arthur C Rettig
Jon K Sekiya
Kevin G Shea
Orrin H Sherman
James R Slauterbeck
Matthew V Smith
Jeffrey T Spang
Ltc Steven J Svoboda
Timothy N Taft
Joachim J Tenuta
Edwin M Tingstad
Armando F Vidal
Darius G Viskontas
Richard A White
James S Williams
Michelle L Wolcott
Brian R Wolf
James J York

Language

English

Publication Date

3-1-2023

Journal

The American Journal of Sports Medicine

DOI

10.1177/03635465231151389

PMID

36734487

PMCID

PMC10338044

PubMedCentral® Posted Date

3-1-2024

PubMedCentral® Full Text Version

Author MSS

Abstract

Background: Meniscal and chondral damage is common in the patient undergoing revision anterior cruciate ligament (ACL) reconstruction.

Purpose: To determine if meniscal and/or articular cartilage pathology at the time of revision ACL surgery significantly influences a patient's outcome at 6-year follow-up.

Study design: Cohort study; Level of evidence, 3.

Methods: Patients undergoing revision ACL reconstruction were prospectively enrolled between 2006 and 2011. Data collection included baseline demographics, surgical technique, pathology, treatment, and scores from 4 validated patient-reported outcome instruments: International Knee Documentation Committee (IKDC), Knee injury and Osteoarthritis Outcome Score (KOOS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and Marx Activity Rating Scale. Patients were followed up at 6 years and asked to complete the identical set of outcome instruments. Regression analysis assessed the meniscal and articular cartilage pathology risk factors for clinical outcomes 6 years after revision ACL reconstruction.

Results: An overall 1234 patients were enrolled (716 males, 58%; median age, 26 years). Surgeons reported the pathology at the time of revision surgery in the medial meniscus (45%), lateral meniscus (36%), medial femoral condyle (43%), lateral femoral condyle (29%), medial tibial plateau (11%), lateral tibial plateau (17%), patella (30%), and trochlea (21%). Six-year follow-up was obtained on 79% of the sample (980/1234). Meniscal pathology and articular cartilage pathology (medial femoral condyle, lateral femoral condyle, lateral tibial plateau, trochlea, and patella) were significant drivers of poorer patient-reported outcomes at 6 years (IKDC, KOOS, WOMAC, and Marx). The most consistent factors driving outcomes were having a medial meniscal excision (either before or at the time of revision surgery) and patellofemoral articular cartilage pathology. Six-year Marx activity levels were negatively affected by having either a repair/excision of the medial meniscus (odds ratio range, 1.45-1.72; P≤ .04) or grade 3-4 patellar chondrosis (odds ratio, 1.72; P = .04). Meniscal pathology occurring before the index revision surgery negatively affected scores on all KOOS subscales except for sports/recreation (P < .05). Articular cartilage pathology significantly impaired all KOOS subscale scores (P < .05). Lower baseline outcome scores, higher body mass index, being a smoker, and incurring subsequent surgery all significantly increased the odds of reporting poorer clinical outcomes at 6 years.

Conclusion: Meniscal and chondral pathology at the time of revision ACL reconstruction has continued significant detrimental effects on patient-reported outcomes at 6 years after revision surgery.

Keywords

Male, Humans, Adult, Follow-Up Studies, Cohort Studies, Cartilage, Articular, Anterior Cruciate Ligament Injuries, Menisci, Tibial, Osteoarthritis, anterior cruciate ligament (ACL), knee articular cartilage, meniscus, outcomes, revision ACL reconstruction

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