Faculty, Staff and Student Publications

Language

English

Publication Date

7-11-2025

Journal

Medicine

DOI

10.1097/MD.0000000000043326

PMID

40660527

PMCID

PMC12263049

PubMedCentral® Posted Date

7-11-2025

PubMedCentral® Full Text Version

Post-print

Abstract

This study aimed to investigate whether there is difference among various clinical variables, especially blood loss and total drainage volume, among patients with different types of hepatitis undergoing cardiac surgery. A retrospective study was performed on 150 hepatitis patients (127 hepatitis B and 23 hepatitis C) who underwent cardiac surgery at a single cardiovascular center in 2020. Data on their preoperative, intraoperative, and postoperative variables were collected and statistically analyzed to assess the inter-group differences in the following variables: intraoperative blood loss, postoperative drainage volume, proportion of patients treated with blood transfusion, proportion of patients treated with vasoactive drugs, and changes in hepatic and renal function. In terms of the main outcome variables, there was no significant difference with respect to intraoperative blood loss and total postoperative blood loss between the 2 groups (P > .05). The lowest intraoperative hematocrit (HCT) was (26.43 ± 4.98)% and (23.5 ± 3.94)% in the hepatitis B and C groups; a significant difference was observed (P = .01). The proportion of patients requiring red blood cell (RBC) transfusion was 3.90% and 17.40% in the hepatitis B and C groups; a significant difference was also noted (P = .043). Hepatitis C patients had a lower intraoperative minimum HCT and a higher probability of RBC transfusion than hepatitis B patients undergoing cardiac surgery. However, blood loss and the total postoperative blood loss were not found to be associated with any specific type of hepatitis.

Keywords

Humans, Retrospective Studies, Male, Female, Cardiac Surgical Procedures, Middle Aged, Blood Loss, Surgical, Aged, Hepatitis C, Hepatitis B, Hematocrit, Postoperative Hemorrhage, Blood Transfusion, blood loss, cardiac surgery, drainage volume, hepatitis

Published Open-Access

yes

Download

Share

COinS
 
 

To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.