Faculty, Staff and Student Publications
Publication Date
2-1-2025
Journal
British Journal of Haematology
DOI
10.1111/bjh.19939
PMID
39622255
PMCID
PMC11844749
PubMedCentral® Posted Date
2-1-2026
PubMedCentral® Full Text Version
Author MSS
Abstract
Chimeric antigen receptor (CAR)-natural killer (NK)-cell therapy has emerged as a promising strategy in the treatment of haematological malignancies and solid cancers. Leveraging the innate immune properties of NK cells, CAR-NK-cell therapies offer potential advantages for cell therapy, including safety of use in the allogeneic setting and reduced risk of toxicity. This Nutshell provides an overview of the latest advancements in CAR-NK-cell therapy and the challenges that remain.
Keywords
Humans, Killer Cells, Natural, Receptors, Chimeric Antigen, Immunotherapy, Adoptive, Neoplasms
Published Open-Access
yes
Recommended Citation
Hind Rafei and Katayoun Rezvani, "Advances and Challenges in Chimeric Antigen Receptor-Natural Killer Cell Immunotherapy for Cancer" (2025). Faculty, Staff and Student Publications. 6460.
https://digitalcommons.library.tmc.edu/uthgsbs_docs/6460
Graphical Abstract
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