Faculty, Staff and Student Publications

Language

English

Publication Date

1-24-2024

Journal

Current Cardiology Reviews

DOI

10.2174/011573403X263956231129064455

PMID

38275069

PMCID

PMC11071679

PubMedCentral® Posted Date

1-24-2024

PubMedCentral® Full Text Version

Post-print

Abstract

The use of cardioprotective strategies as adjuvants of cardioplegic solutions has become an ideal alternative for the improvement of post-surgery heart recovery. The choice of the optimal cardioplegia, as well as its distribution mechanism, remains controversial in the field of cardiovascular surgery. There is still a need to search for new and better cardioprotective methods during cardioplegic procedures. New techniques for the management of cardiovascular complications during cardioplegia have evolved with new alternatives and additives, and each new strategy provides a tool to neutralize the damage after ischemia/reperfusion events. Researchers and clinicians have committed themselves to studying the effect of new strategies and adjuvant components with the potential to improve the cardioprotective effect of cardioplegic solutions in preventing myocardial ischemia/reperfusion-induced injury during cardiac surgery. The aim of this review is to explore the different types of cardioplegia, their protection mechanisms, and which strategies have been proposed to enhance the function of these solutions in hearts exposed to cardiovascular pathologies that require surgical alternatives for their corrective progression.

Keywords

ischemia/reperfusion, cardiovascular disease, cardioplegia, cardioprotection, cardiac surgery, angiotensins

Published Open-Access

yes

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