Faculty, Staff and Student Publications
Publication Date
6-2-2025
Journal
Journal of Experimental Medicine
DOI
10.1084/jem.20241814
PMID
40152785
PMCID
PMC11952069
PubMedCentral® Posted Date
3-28-2025
PubMedCentral® Full Text Version
Post-print
Abstract
Maladaptive repair following kidney injury leads to the development of kidney disease. In this issue of JEM, Ajay et al. (https://doi.org/10.1084/jem.20231107) uncover the role of breast cancer susceptibility gene 1 (BRCA1) in cell cycle arrest, DNA damage, and cell senescence, preventing maladaptive repair.
Keywords
BRCA1 Protein, Kidney, Regeneration, Animals, Humans, DNA Damage, Cellular Senescence, Cell Cycle Checkpoints
Published Open-Access
yes
Recommended Citation
Kaira A Church, Xunian Zhou, and Raghu Kalluri, "Suppression of BRCA1 Facilitates Kidney Regeneration" (2025). Faculty, Staff and Student Publications. 6826.
https://digitalcommons.library.tmc.edu/uthgsbs_docs/6826
Included in
Bioinformatics Commons, Biomedical Informatics Commons, Genetic Phenomena Commons, Medical Genetics Commons, Oncology Commons