Faculty, Staff and Student Publications
Publication Date
9-1-2024
Journal
Protein & Cell
Abstract
Cell death resistance represents a hallmark of cancer. Recent studies have identified metabolic cell death as unique forms of regulated cell death resulting from an imbalance in the cellular metabolism. This review discusses the mechanisms of metabolic cell death-ferroptosis, cuproptosis, disulfidptosis, lysozincrosis, and alkaliptosis-and explores their potential in cancer therapy. Our review underscores the complexity of the metabolic cell death pathways and offers insights into innovative therapeutic avenues for cancer treatment.
Keywords
Humans, Ferroptosis, Neoplasms, Cell Death, Animals, Copper
Comments
PMID: 38428031