Faculty, Staff and Student Publications
Publication Date
9-1-2024
Journal
Protein & Cell
Abstract
Cell death resistance represents a hallmark of cancer. Recent studies have identified metabolic cell death as unique forms of regulated cell death resulting from an imbalance in the cellular metabolism. This review discusses the mechanisms of metabolic cell death-ferroptosis, cuproptosis, disulfidptosis, lysozincrosis, and alkaliptosis-and explores their potential in cancer therapy. Our review underscores the complexity of the metabolic cell death pathways and offers insights into innovative therapeutic avenues for cancer treatment.
Keywords
Humans, Ferroptosis, Neoplasms, Cell Death, Animals, Copper
DOI
10.1093/procel/pwae003
PMID
38428031
PMCID
PMC11365558
PubMedCentral® Posted Date
March 2024
PubMedCentral® Full Text Version
Post-print
Published Open-Access
yes
Included in
Biochemical Phenomena, Metabolism, and Nutrition Commons, Bioinformatics Commons, Biomedical Informatics Commons, Endocrine System Diseases Commons, Oncology Commons
Comments
PMID: 38428031