Faculty, Staff and Student Publications

Publication Date

3-19-2023

Journal

Cancers

Abstract

Radiotherapy for pediatric brain tumors is associated with reduced white matter structural integrity and neurocognitive decline. Superior cognitive outcomes have been reported following proton radiotherapy (PRT) compared to photon radiotherapy (XRT), presumably due to improved sparing of normal brain tissue. This exploratory study examined the relationship between white matter change and late cognitive effects in pediatric brain tumor survivors treated with XRT versus PRT. Pediatric brain tumor survivors treated with XRT (

Keywords

pediatric brain tumor, proton radiotherapy, white matter, diffusion tensor imaging, late effects

DOI

10.3390/cancers15061844

PMID

36980730

PMCID

PMC10047305

PubMedCentral® Posted Date

March 2023

PubMedCentral® Full Text Version

Post-print

Published Open-Access

yes

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