Case Studies in Heritable Vascular Disease: Proceedings of the UTHealth Houston Multidisciplinary Aortic Conference

Authors

Milan Jaiswal
Lucas Ribe
Rana O Afifi
Yuki Ikeno
Alana C Cecchi
Bihong Zhao
Akiko Tanaka
Gustavo S Oderich
L Maximilian Buja
Dianna M Milewicz
Siddharth K Prakash
Anthony L Estrera

Language

English

Publication Date

2-1-2025

Journal

Journal of Vascular Surgery Cases, Innovations and Techniques

DOI

10.1016/j.jvscit.2024.101684

PMID

39760020

PMCID

PMC11699403

PubMedCentral® Posted Date

11-16-2024

PubMedCentral® Full Text Version

Post-print

Abstract

Heritable thoracic aortic disease is caused by dominantly inherited mutations in more than a dozen genes, including TGFB2 mutations that cause Loeys-Dietz syndrome. McGovern Medical School at UTHealth Houston convenes a regular conference that includes cardiothoracic and vascular surgeons, cardiologists, geneticists, radiologists, and pathologists to formulate multidisciplinary approaches for the management of complex heritable thoracic aortic disease cases. In this report, we highlight the unique management of individuals with distinct presentations of Loeys-Dietz syndrome owing to TGFB2 mutations.

Keywords

Heritable thoracic aortic diseases, HTAD, TGFB2, Loeys-Dietz syndrome, LDS, Genetic testing, Aortic dissection

Published Open-Access

yes

Recommended Citation

Jaiswal, Milan; Ribe, Lucas; Afifi, Rana O; et al., "Case Studies in Heritable Vascular Disease: Proceedings of the UTHealth Houston Multidisciplinary Aortic Conference" (2025). Faculty, Staff and Student Publications. 1102.
https://digitalcommons.library.tmc.edu/uthmed_docs/1102