The Health-Promoting Effects and The Mechanism of Intermittent Fasting

Authors

Simin Liu
Min Zeng
Weixi Wan
Ming Huang
Xiang Li
Zixian Xie
Shang Wang
Yu Cai

Language

English

Publication Date

1-1-2023

Journal

Journal of Diabetes Research

DOI

10.1155/2023/4038546

PMID

36911497

PMCID

PMC10005873

PubMedCentral® Posted Date

May 2023

PubMedCentral® Full Text Version

Post-Print

Abstract

Intermittent fasting (IF) is an eating pattern in which individuals go extended periods with little or no energy intake after consuming regular food in intervening periods. IF has several health-promoting effects. It can effectively reduce weight, fasting insulin levels, and blood glucose levels. It can also increase the antitumor activity of medicines and cause improvement in the case of neurological diseases, such as memory deficit, to achieve enhanced metabolic function and prolonged longevity. Additionally, IF activates several biological pathways to induce autophagy, encourages cell renewal, prevents cancer cells from multiplying and spreading, and delays senescence. However, IF has specific adverse effects and limitations when it comes to people of a particular age and gender. Hence, a more systematic study on the health-promoting effects and safety of IF is needed. This article reviewed the research on the health-promoting effects of IF, providing a theoretical basis, direction for subsequent basic research, and information related to the clinical application of IF.

Keywords

Humans, Intermittent Fasting, Fasting, Feeding Behavior, Energy Intake, Diet, Reducing

Published Open-Access

yes

Recommended Citation

Liu, Simin; Zeng, Min; Wan, Weixi; et al., "The Health-Promoting Effects and The Mechanism of Intermittent Fasting" (2023). Faculty, Staff and Student Publications. 211.
https://digitalcommons.library.tmc.edu/uthshis_docs/211