Faculty, Staff and Student Publications
Language
English
Publication Date
1-1-2025
Journal
AMIA Summits on Translational Science Proceedings
PMID
40502219
PMCID
PMC12150692
PubMedCentral® Posted Date
6-10-2025
PubMedCentral® Full Text Version
Post-print
Abstract
Sudden Unexpected Death in Epilepsy (SUDEP) is a major cause of death for epilepsy patients having uncontrolled seizures. Understanding the complex neural circuits within the central nervous system is crucial for understanding the mechanisms underlying cardiorespiratory regulation, particularly in the context of SUDEP. This study explores the potential of GPT-4o, a cutting-edge language model, to automate the extraction of neural projections from scientific literature. We developed prompts to extract neuroscientific structures, extract projections, and perform synonym harmonization. Applying the approach to four neuroscientific articles, the method extracted 205 projections. A random sample of 100 projections identified was handed over to a domain expert for review where 95 were found to be correct. Therefore, GPT-4o was determined to be accurate in parsing complex scientific texts in extracting neural projections. Future work will involve extracting additional entities like techniques and species information for the projections identified.
Published Open-Access
yes
Recommended Citation
Abeysinghe, Rashmie; Jowah, Gorbachev; Cui, Licong; et al., "Leveraging GPT-4o for Automated Extraction of Neural Projections from Scientific Literature" (2025). Faculty, Staff and Student Publications. 394.
https://digitalcommons.library.tmc.edu/uthshis_docs/394